Fermenteeritud köögiviljaekstrakti (OM-X) uuringud

Uuring (kõik uuringud koos)

1. Inimeste peal läbi viidud kliinilised fermenteeritud köögiviljaekstrakti (OM-X) uuringud

• Kehakaalu suurenemise või kaalukaotuse eest vastutavate bakterite tasakaalu parandamine (Collabrorative research with Hokkano University of Science (2018))
• Maksimaalse VO₂ taseme suurendamine (Journal of Appleid Nutrition 53, 1-6 (2003))
• Kõhukinnisuse leevenemine (The 69ᵗʰ Annual Meeting of Japan Society of Nutrition and Food Science (2015))
• Kopsupõletiku leevendamine (3ʳᵈ Asian Congress of Pediatric Infectious Diseases and 13^th Pediatric Infectious Diseases Society of The Philippines Annual Convention (2006))
• Kõhulahtisuse paranemine (1ˢᵗ Congress of Asian Society for Pedriatic Research (2005))
• Luutiheduse suurenemine (Kurashiki University of Science and the Arts 3, 131-144 (1998)) 
• Dengue´i palaviku leevenemine (Asian Conference on Diorrhoeal Diseases and Nutrition (2006))
• Kuseteede infektsiooni leevendamine
• Alatoitumise parandamine
• Inimohutuse test
• Üleannustamise test inimeste puhul

2. Loomadel läbiviidud uuringud fermenteeritud köögiviljaekstrakti OM-X osas

• Allergiavastane toime (Natural Product Communications. 10, 1597-1601 (2015))
• Lihaste vastupidavuse parandamine (Annual Conference of the Japan Society for Bioscience, Biotechnoloy and Agrochemistry (2015))  
• Väsimusevastane toime (Annual Conference of the Japan Society for Bioscience, Biotechnoloy and Agrochemistry (2015)) 
• Maksafunktsioonide halvenemise ennetamine (The 138ᵗʰ Annual Meeting of the Pharmaceutical Society of Japan (2018))
• Kollageenitaseme vähendamise ennetamine (Collaborative research with Hokkaido University of Science (2018))
• Kandidoosi paranemine (Joint research with The University of Lille, France (2014))
• Soolestiku mikrobioota tasakaalu paranemine (Joint research with Kinki University (2012))

3. In vitro uuringud, mis on seotud fermenteeritud köögiviljaekstraktiga OM-X

• Metaboloomianalüüs 
• Prebiootiline efekt
• Aktiivsete koostisainete akumulatsioon (Annual Conference of the Japan Society for Bioscience, Biotechnology and Agrochemistry (2010))
• Antioksüdant, ACE-inhibeeriv toime (Annual Conference of the Japan Society for Bioscience, Biotechnology and Agrochemisty (2010))
• Antibakteriaalne aktiivsus (Pseudomonas aeruginosa)
• D-aminohapete analüüs
• GLP-1 stimuleeriv toime (Intregrative Molecular Medicine, 4, 1-5 (2017))

1. OM-X®, a Fermented Vegetables Extract, Facilitates Muscle Endurance Capacity in Swimming Exercise Mice
2. Fermented vegetable and fruit extract (OM-X®) stimulates murine gastrointestinal tract cells and RAW264.7 cells in vitro and regulates liver gene expression in vivo
3. OM-X®, fermented vegetables extract suppresses the type I allergy
4. Evaluation of therapeutic properties of fermented vegetables extract (OM-X) in the model of colitis induced by Citrobacter rodentium in mice
5. Complete sequence analysis of two cryptic plasmids from Bifidobacterium kashiwanohense JCM 15439 (type strain) isolated from healthy infant feces
6. Safety and tolerability of Dr Ohhira’s OM-X Capsules in healthy volunteers
7. Immunomodulatory effects of heat-killed Enterococcus faecalis TH10 on murine macrophage cells.
8. Identification of 3-phenyllactic acid as a possible antibacterial substance produced by Enterococcus faecalis TH10.
9. Effects of fermentation product of herbs by lactic acid bacteria against phytopathogenic filamentous fungi and the growth of host plants.
10. The influences of lactic acid bacteria (OM-X) on bone structure.
11. Purification of anti Escherichia coli O-157 components produced by Enterococcus faecalis TH10, an isolate from Malaysian fermented food, temph.
12. The influences on the VO2max of athlete with taking lactic acid bacteria (OM-X)
13. Antimicrobial activity against methicillin-resistant Staphylococcus aureus in the culture broth of Enterococcus faecalis TH10, an isolate from Malaysian fermentation food, Temph.
14. Effect of cultural conditions on the fumarate metabolism in Lactobacillus delbrueckii.
15. Screening for lactic acid bacteria transforming fumarate to L-malate and some properties of selected strains.
16. Distribution and biochemical properties of lactic acid bacteria from traditional fermented foods in Southeast Asia.
17. Distribution of lactic acid bacteria from traditional fermented foods in Southeast Asia.
18. Biochemical properties of lactic acid bacteria from traditional fermented foods in Southeast Asia. 2. Protein hydrolysis and aroma production of lactic acid bacteria from traditional fermented foods in Southeast Asia.
19. Isolation and identification of lactic acid bacteria from traditional fermented sauce in Southeast Asia.
20. Biochemical properties of lactic acid bacteria from traditional fermented foods in Southeast Asia. 1. Salt-, acid-, heat-tolerance and acid-production of lactic acid bacteria from traditional fermented foods in Southeast Asia.
21. Identification of lactic acid bacteria isolated from traditional side-dish fermented foods in Southeast Asia.
22. The isolation of lactic acid bacteria from traditional side-dish fermented foods in Southeast Asia.
23. The isolation and identification of lactic acid bacteria from traditional alcoholic drink in Southeast Asia.
24. The traditional fermented foods and their microflora in Southeast Asia.
25. The isolation and identification of lactic acid bacteria from naturally fermented wild plants and fruits.
26. Studies on fermented vegetable extract (OM-X)

1. Oral supplementation of specific collagen peptides has beneficial effects on human skin physiology: a double-blind, placebo-controlled study
2. Oral intake of specific bioactive collagen peptides reduces skin wrinkles and increases dermal matrix synthesis
3. Oral supplementation with specific bioactive collagen peptides improves nail growth and reduces symptoms of brittle nails
4. Daily oral consumption of hydrolyzed type 1 collagen is chondroprotective and anti-inflammatory in murine posttraumatic osteoarthritis
5. 24-Week study on the use of collagen hydrolysate as a dietary supplement in athletes with activity-related joint pain
6. Role of collagen hydrolysate in bone and joint disease
7. Daily oral supplementation with collagen peptides combined with vitamins and other bioactive compounds improves skin elasticity and has a beneficial effect on joint and general wellbeing
8. Effects of Native Type II Collagen Treatment on Knee Osteoarthritis: A Randomized Controlled Trial